AB01
A randomised trial of epirubicin and cyclosphamide versus epirubicin and paclitaxel in the treatment of women with metastatic breast cancer
AXIS
A randomised trial of post-operative portal vein infusion of fluorouracil vs surgery alone for colorectal cancer, and of peri-operative radiotherapy vs no radiotherapy for rectal cancer
Bladder cancer: (2005) Adjuvant chemotherapy, systematic review and IPD meta-analysis
Adjuvant chemotherapy in invasive bladder cancer: a systematic review and meta-analysis of individual patient data
Bladder cancer: (2022) Adjuvant chemotherapy, systematic review and IPD meta-analysis
Adjuvant Chemotherapy for Muscle-invasive Bladder Cancer: A Systematic Review and Meta-analysis of Individual Participant Data from Randomised Controlled Trials
Bladder cancer: Neoadjuvant chemotherapy, systematic review and IPD meta-analysis
Neoadjuvant chemotherapy in invasive bladder cancer: update of a systematic review and meta-analysis of individual patient data
BLT
Big Lung Trial: A randomised trial to determine the value of cisplatin-based chemotherapy for all patients with non-small cell lung cancer
BO01
Two adjuvant chemotherapy regimens in the treatment of osteosarcoma
BO02
A randomised pilot study of two drug combinations in patients with osteosarcoma
BO03
A randomised trial of two-drug versus multi-drug chemotherapy in the treatment of operable osteosarcoma
BO04
A phase II study of cisplatin, ifosfamide and doxorubicin (PIA) chemotherapy in operable primary, axial skeletal and metastatic osteosarcoma
BO05
A phase II study of Adriamycin and cisplatin in spindle cell sarcoma of bone other than osteosarcoma
BO06
A randomised trial of chemotherapy with or without granulocyte colony stimulating factor (G-CSF) in operable osteosarcoma
BR01
Medical Research Council Study of Misonidazole in Conjunction with Radiotherapy for the Treatment of Malignant Gliomas (Astrocytomas) Grades III and IV
BR02
A Medical Research Council Study of Two Radiotherapy Dose Regimens for the Treatment of Adult Patients with Malignant Gliomas Grades III and IV
BR03
A study of CCNU with and without benznidazole in the treatment of recurrent grades 3 and 4 astrocytomas
BR04
Randomised trial on the efficacy of radiotherapy for cerebral low-grade glioma in the adult: EORTC 22845 randomised trial
BR05
A randomised trial of adjuvant chemotherapy in high grade malignant glioma
BR12
Temozolomide versus PCV chemotherapy in the treatment of recurrent malignant glioma
BR13
Primary chemotherapy with temozolomide vs. radiotherapy in patients with low grade glioma after stratification for genetic 1p loss: a phase III study. Intergroup Study (EORTC 22033-26033)
BR14
Phase III trial on concurrent and adjuvant temozolomide chemotherapy in non-1p/19q deleted anaplastic glioma. The CATNON Intergroup trial
Cancer: Stem cell transplantation, systematic review and aggregate data meta-analysis
Autologous stem cell transplantation for malignancy: a systematic review of the literature
Cervical cancer: Chemoradiotherapy, systematic review and IPD meta-analysis
Concomitant chemoradiotherapy versus radiotherapy for cervical cancer: a systematic review and meta-analysis of individual patient data.
Cervical cancer: hydroxyurea and radiotherapy, systematic review and aggregate data meta-analysis
Concomitant hydroxyurea plus radiotherapy versus radiotherapy for carcinoma of the uterine cervix: a systematic review
Cervical cancer: Neoadjuvant chemotherapy, systematic review and IPD meta-analysis
Neoadjuvant chemotherapy for locally advanced cervical cancer: a systematic review and meta-analysis of individual patient data
CHART (CH01)
A randomised multicentre trial of continuous hyperfractionated accelerated radiotherapy (CHART) versus conventional radiotherapy
CHART (CH02)
A randomised multicentre trial of continuous hyperfractionated accelerated radiotherapy (CHART) versus conventional radiotherapy in head and neck cancer
CHORUS
A large phase III multi-centre randomised trial to determine the impact of timing of surgery and chemotherapy in newly diagnosed patients with advanced epithelial ovarian, primary peritoneal or fallopian tube cancer
COIN, CR10
A three arm randomised controlled trial comparing either continuous chemotherapy plus cetuximab, or intermittent chemotherapy with standard continuous palliative combination chemotherapy with oxaliplatin and a fluoropyrimidine in first line treatment of metastatic colorectal cancer
COIN-B
A two-arm phase II randomised trial of intermittent chemotherapy plus continuous cetuximab and of intermittent chemotherapy plus intermittent cetuximab in first line treatment of patients with K-ras-normal (wild-type) metastatic colorectal cancer
Colorectal cancer: Anti-EGFR treatment, systematic review and aggregate data meta-analysis
Does anti-EGFR therapy improve outcome in advanced colorectal cancer? A systematic review and meta-analysis
CR09/FOCUS 2
Drug treatment for bowel cancer: making the best choices when a milder treatment is needed
Endometrial cancer: Chemotherapy, systematic review and aggregate data meta-analysis
Chemotherapy for advanced, recurrent or metastatic endometrial carcinoma
EURAMOS-1
A randomised trial of the European and American Osteosarcoma Study group to optimize treatment strategies for resectable osteosarcoma based on the histological response to pre-operative chemotherapy
FOCUS-3
A study to determine the feasibility of molecular selection of therapy using KRAS, BRAF and topo-1 in patients with metastatic or locally advanced colorectal cancer
FOCUS4
A molecularly-stratified randomised controlled trial programme for patients with advanced colorectal (bowel) cancer
Glioma: Chemotherapy, systematic review and IPD meta-analysis
Chemotherapy in adult high-grade glioma: a systematic review and meta-analysis of individual patient data from 12 randomised trials
ICON6
A double-blind, placebo-controlled, three arm randomised multi-centre GCIG trial of AZD2171 in patients with ovarian cancer
ICON7
Chemotherapy with or without bevacizumab for ovarian cancer, primary peritoneal cancer or fallopian tube cancer
ICON8
An international phase III randomised trial of dose fractionated chemotherapy compared to standard three weekly chemotherapy, following immediate primary surgery or as part of delayed primary surgery, for women with newly diagnosed epithelial ovarian, fallopian tube or primary peritoneal cancer
ICON8B
A phase 3 randomised trial investigating the combination of dose-fractionated chemotherapy and bevacizumab compared to either strategy alone for the first-line treatment of women with newly diagnosed high-risk stage III-IV epithelial ovarian, fallopian tube or primary peritoneal cancer
INCH
Induction chemotherapy and CHART in non-small cell lung cancer
LU09
Three versus six courses of etoposide, cyclophosphamide, methotrexate and voncristine versus six courses of etoposide and ifosfamide in small cell lung cancer
LU10
A phase II trial of alternating chemotherapy and radiotherapy in small cell lung cancer
LU11
A randomised trial of post-operative radiotherapy in non-small cell lung cancer
LU12
A randomised trial of 4-drug vs less intensive 2-drug chemotherapy in the palliative treatment of patients with non-small cell lung cancer and a poor prognosis
LU13
A randomised trial of palliative 2-fraction vs more intensive 13-fraction radiotherapy for patients with inoperable NSCLC and a good performance status
LU14
Adding GCSF (lenograstim) to chemotherapy to try and increase the dose intensity of chemotherapy given to patients with small cell lung cancer
LU15
Adding GCSF (filgrastim) to chemotherapy to try and increase the dose intensity of chemotherapy given to patients with small cell lung cancer
LU16
A randomised trial of oral etoposide vs intravenous multi-drug chemotherapy in the palliative treatment of patients with small cell lung cancer and a poor prognosis
LU17
A randomised trial of supportive treatment with or without immediate thoracic radiotherapy in the prevention and palliation of symptoms in patients with inoperable non-small cell lung cancer and minimal thoracic symptoms
LU18
A randomised controlled clinical trial of endobronchial treatment versus external beam radiotherapy in the management of endotracheal or endobronchial obstruction by lung cancer
LU19
A randomised controlled intensification clinical trial of chemotherapy with or without recombinant human granulocyte colony stimulating factor (G-CSF) in small-cell lung cancer
LU20
A randomised trial of neo-adjuvant chemotherapy followed by resection versus radiotherapy in patients with T3, N1, M0 or T1-3, N2, M0 non-small cell lung cancer (NSCLC)
LU21
A randomised clinical trial of isosfamide, carboplatin and etoposide with mid-cycle vincristine (ICE-V) versus standard practice chemotherapy in patient with small-cell lung cancer (SCLC) and good performance status
LU22
Surgical resection with or without pre-operative chemotherapy in patients with operable non-small cell lung cancer
Lung cancer: chemotherapy and supportive care, a systematic review and IPD meta-analysis
Chemotherapy and supportive care versus supportive care for advanced non-small cell lung cancer: A systematic review and meta-analysis of individual patient data
Lung cancer: chemotherapy, surgery, radiotherapy, two systematic reviews and IPD meta-analyses
Adjuvant chemotherapy and surgery (with or without radiotherapy) versus surgery (with or without radiotherapy) for non-small cell lung cancer: Two systematic reviews and meta-analyses of individual patient data
Lung cancer: post-operative radiotherapy, a systematic review and IPD meta-analysis
Postoperative radiotherapy for non‐small cell lung cancer
Lung cancer: preoperative chemotherapy, systematic review and IPD meta-analysis
Preoperative chemotherapy for non-small cell lung cancer: a systematic review and meta-analysis of individual participant data
Lung cancer: TKI inhibitors, systematic review and aggregate data meta-analysis
Should tyrosine kinase inhibitors be considered for advanced non-small cell lung cancer with wild type EGFR? Two systematic reviews and meta-analyses of randomised trials
LY06
A multicentre evaluation of National Cancer Institute protocol 89-C-41 (with minor modifications) in Burkitt or Burkitt-like non-Hodgkin lymphoma
LY09
A randomised trial of therapy for advanced Hodgkin lymphoma
MESO-1
A randomised trial of active symptom control with or without chemotherapy in patients with malignant pleural mesothelioma
OE02
Randomised controlled clinical trial of surgery with or without pre-operative chemotherapy in the treatment of respectable cancer of the oesophagus
OE05
A randomised controlled trial comparing standard chemotherapy followed by resection versus ECX chemotherapy followed by resection in patients with resectable adenocarcinoma of the oesophagus
Oesophageal cancer: Preoperative radiotherapy, a systematic review and IPD meta-analysis
Preoperative radiotherapy for oesophageal carcinoma: systematic review and meta-analysis of individual patient data
OV05
Early treatment based on CA125 levels alone versus delayed treatment based on conventional clinical indicators
OV07
Phase III study of Erlotinib vs. observation in ovarian cancer
PATCH (PR09)
A randomised controlled trial of transcutaneous oestrogen patches versus LHRH agonists in prostate cancer
PCI
A randomised trial of prophylactic cranial irradiation in patients with limited disease SCLC and a complete response after induction therapy
PR04
A randomised trial of oral sodium clodronate versus a matching placebo in patients with locally advanced prostatic adenocarcinoma
PR05
A randomised trial of oral sodium clodronate versus a matching placebo in patients with metastatic prostate adenocarcinoma.
PR06
Radical prostatectomy vs radical radiotherapy vs no immediate treatment for localised prostate cancer: a randomised controlled trial
PR07
A randomised trial of hormone therapy plus radical radiotherapy versus hormone therapy alone in non-metastatic prostate cancer
PROMIS
Prostate MRI Imaging Study - Evaluation of multi-parametric magnetic imaging in the diagnosis and characterisation of prostate cancer
QUARTZ
Quality of life after treatment of brain metastases
RADICALS
Radiotherapy and androgen deprivation in combination after local surgery. A randomised controlled trial in prostate cancer
RAMPART
Renal Adjuvant MultiPle Arm Randomised Trial: An international investigator-led phase III multi arm multi stage multi-centre randomised controlled platform trial of adjuvant therapy in patients with resected primary renal cell carcinoma (RCC) at high or intermediate risk of relapse
RE04
A randomised controlled trial of Interferon-a, Interleukin-2 and 5-Fluorouracil vs Interferon-a alone in patients with advanced renal cell carcinoma
RT01
A randomised controlled trial of high dose versus standard dose conformal radiotherapy for localised prostate cancer
Sarcoma: adjuvant chemotherapy, systematic review and IPD meta-analysis
Adjuvant chemotherapy for localised resectable soft-tissue sarcoma of adults: meta-analysis of individual participant data
SORCE
A multi-centre phase III double-blind placebo-controlled study designed to examine the efficacy and tolerability of sorafenib (Nexavar) in patients with resected (total or partial) primary renal cell carcinoma (RCC) at high or intermediate risk of relapse
ST02
A randomised, controlled trial of pre- and post-operative chemotherapy in patients with operable gastric and lower oesophageal cancer
ST03
A randomised phase II/III trial of perioperative chemotherapy with or without bevacizumab in operable oesophagogastric adenocarcinoma and a feasibility study evaluating lapatinib in HER-2 positive oesophagogastric adenocarcinomas and (in selected centres) MRI and PET/CT sub-studies
STAMPEDE
Systemic Therapy in Advancing or Metastatic Prostate cancer: Evaluation of Drug Efficacy
STOPCAP M0, bisphosphonates, systematic review and aggregate data meta-analysis
Addition of bisphosphonates to standard of care in men with localised, hormone-sensitive prostate cancer: a systematic review and meta-analyses of aggregate data
STOPCAP M0, docetaxel, systematic review and aggregate data meta-analysis
Addition of docetaxel to standard of care in men with localised hormone-sensitive prostate cancer: a systematic review and meta-analyses of aggregate data
STOPCAP M1, abiraterone, systematic review and aggregate data meta-analysis
Addition of abiraterone to standard of care in men with metastatic hormone-sensitive prostate cancer: a systematic review and meta-analyses of aggregate data
STOPCAP M1, aggregate data network meta-analysis
What is the optimal systemic treatment of men with metastatic, hormone-sensitive prostate cancer? a systematic review and network meta-analyses of aggregate data
STOPCAP M1, bisphosphonates, systematic review and aggregate data meta-analysis
Addition of bisphosphonates to standard of care in men with metastatic, hormone-sensitive prostate cancer: a systematic review and meta-analyses of aggregate data
STOPCAP M1, docetaxel, systematic review and aggregate data meta-analysis
Addition of docetaxel to standard of care in men with metastatic, hormone-sensitive prostate cancer: a systematic review and meta-analyses of aggregate data
STOPCAP M1, prostate RT, systematic review and aggregate data meta-analysis
Addition of prostate radiotherapy to ADT in men with metastatic, hormone-sensitive prostate cancer: a systematic review and meta-analyses of aggregate data
TE04
A prospective study of surveillance in stage 1 non-seminomatous testicular tumours
TE05
Adjuvant bleomycin, etoposide and cisplatin (BEP) in the treatment of "high risk" stage I non-seminomatous germ cell tumours
TE08
A randomised trial of two vs five CT scans in the surveillance of patients with stage I non-seminomatous germ cell tumours of the testis
TE09
Randomised trial of carboplatin- vs cisplatin based chemotherapy for good prognosis metastatic non-seminomatous germ cell tumours
TE11
A prospective study of risk factors for carcinoma in situ of the contralateral testis in patients with testicular cancer
TE12
A randomised trial of single agent carboplatin vs etoposide and cisplatin for advanced metastatic seminoma
TE13
A randomised trial of BEP (bleomycin, etoposide, cisplatin) vs BOP/VIP-B (bleomycin, vincristine, cisplatin, etoposide, ifosfamide cisplatin, bleomycin) and of the same regimens with or without G-CSF in poor prognosis metastatic germ cell tumours
TE14
Prognostic factors for patients with advanced seminoma treated with platinum based chemotherapy
TE15
Prognostic factors in patients progressing after platinum-based chemotherapy for metastatic non-seminomatous germ cell tumours
TE16
Post chemotherapy residual masses in germ cell tumour patients
TE17
Adjuvant bleomycin, vincristine and cisplatin for high-risk stage I non-seminomatous germ cell tumours
TE20
A randomised trial of 3 cycles of BEP versus 3 cycles of BEP plus 1 cycle of EP and the 3-day versus the 5-day schedule in good prognosis metastatic germ cell cancer
TE21 (EORTC 30983)
A randomised trial of BEP vs Taxol-BEP in histologically proven metastatic germ cell cancer with intermediate prognosis
TE23
A randomised phase II trial of intensive induction chemotherapy (CBOP/B15EP) and standard BEP chemotherapy in poor prognosis male germ cell tumours
TRANSORCE
A study to collect blood and tissue samples from consenting patients who have been diagnosed with kidney cancer
TRISST (MRC TE24)
Trial of imaging and schedule in seminoma testis
UKCTOCS
UK Collaborative Trial of Ovarian Cancer Screening
UKOPS
UK Ovarian Cancer Population Study