In 2012, the MRC CTU at UCL adopted a policy that all our clinical studies should have PPI. To ensure that the involvement was relevant and useful rather than tokenistic, we have worked to embed high quality PPI in the culture of the Unit. This poster presented by Annabelle South at the International Clinical Trials Methodology Conference (2022) describes our processes to achieve this and includes the results of a recent survey of trial staff assessing our progress.
Read more here.
Meeting discussion report exploring PPI in trials looking at short term conditions – e.g. pneumonia.
This guidance aims to explain how the Patient Information Sheet template can be adjusted for alternative requirements.
This gives advice to researchers who design and carry out systematic reviews on how best to involve patients and the public. The guidance is published by INVOLVE.
Advice to researchers who design and conduct clinical trials on how best to involve patients and the public. The guidance is published by INVOLVE.
Advice on how to involve people affected by cancer in MRC CTU at UCL cancer trials and studies.
This paper offers recommendations for enhancing PPI in future Multiple Sclerosis clinical trials.
Clinical Trials Units are encouraged to integrate Patient and Public Involvement (PPI) into all aspects of trial design, running and oversight. This research explored the induction and training of PPI Contributors joining trial oversight committees and was used to update the MRC CTU at UCL induction pack for new PPI Contributors.
This paper explores how participants have been actively involved in some of our clinical trials and the impact this has had.
Case studies that describe PPI in clinical trials, meta-analysis and an observational study. It shows how people were involved and the impact this had.
This survey, undertaken in 2012, showed that most of our researchers felt that there were clear benefits from involving patients and the public in the design and running of trials. As a result of this survey, the PPI Group increased its efforts to get PPI established across all trials at the MRC CTU.
Describes how we involved women affected by cervical cancer in a systematic review and meta-analysis of individual patient data to evaluate treatments for cervical cancer, and the impact this had on the research, the researchers and the women affected by cervical cancer who got involved.
This paper reports the evaluation of participant and community involvement in the "PROUD" trial.