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Optimal Clinical Trials Platform for Progressive Multiple Sclerosis

A randomised trial of dolutegravir-based antiretroviral therapy vs. standard of care in children with HIV infection starting first-line or switching to second-line antiretroviral therapy.

Randomised controlled clinical trial of surgery with or without pre-operative chemotherapy in the treatment of respectable cancer of the oesophagus

A randomised controlled trial comparing standard chemotherapy followed by resection versus ECX chemotherapy followed by resection in patients with resectable adenocarcinoma of the oesophagus

Preoperative radiotherapy for oesophageal carcinoma: systematic review and meta-analysis of individual patient data

Early treatment based on CA125 levels alone versus delayed treatment based on conventional clinical indicators

Phase III study of Erlotinib vs. observation in ovarian cancer