Multi-centre Obstructive Sleep Apnoea Interventional Cardiovascular trial

Can pumping air into the nose help people with mild sleep disorder?

What is this study about?

Obstructive sleep apnoea (OSA) is a type of sleep disorder. It happens when air fails to get to the lungs when people are asleep. This causes the person to wake up many times through the night. If untreated, it can cause illnesses such as high blood pressure, heart disease and stroke. Doctors treat severe OSA with something called nasal continuous positive airway pressure (NCPAP). NCPAP consists of a machine which pumps air into your nose, via a mask. This helps air get to the lungs and reduces blood pressure. The MOSAIC trial aims to find out whether NCPAP can help to reduce the risk of heart disease in people with milder forms of OSA. It is being run in partnership with the Oxford Sleep Unit at the Churchill Hospital, Oxford.

Type of study

Randomised trial

Contact details

Who is funding the study?

British Heart Foundation and ResMed UK.

When is it taking place?

This trial completed recruitment in August 2009.

Where is it taking place?

10 sites (Oxford, Reading, Taunton, Vancouver, Edinburgh, Leeds, York, Wolverhampton and two in London)

Who is included?

People aged between 45 and 75 with mild to moderate obstructive sleep apnoea.