Our research at The Union World Conference on Lung Health
13 Nov 2023
This week, researchers from around the world will gather in Paris for The Union World Conference on Lung Health, held from 15-18 November in Paris, France. The theme for 2023 is 'Transforming evidence into practice', emphasising the need to implement evidence-based health policies and decisions.
The MRC Clinical Trials Unit at UCL and our collaborators from other institutions will showcase the latest advances from our tuberculosis (TB) clinical trials, including SURE, STREAM Stage 2, TB-CHAMP and PARADIGM4TB, as well as work on developing a new conceptual framework for the different states of early TB.
Details of the presentations are summarised below. All times are CET.
Working group side meetings:
| Day | Session | Title | Presenter |
| Tuesday 14 November | Child and Adolescent TB Working Group (World Health Organization) | SURE trial update and challenges with recruitment and diagnosis | Julie Hyunh |
| Wednesday 15 November | Maternal and Child TB Working Group | Clinico-radiological spectrum and results of CSF mycobacterial testing in pediatric tubercular meningitis at diagnosis- baseline findings from the SURE trial | Suvasini Sharma |
Union conference main programme:
| Day | Time | Session | Title | Presenter |
| Wednesday 15 November | 3:37 PM | OA06: Safety of regimens for R-R |
Predictive analyses of QT prolongation from ECG monitoring in the STREAM Stage 2 trial |
Gareth Hughes |
| 3:47 PM | SP06: Progress and innovation in developing shorter treatment regimens for people with TB | Duration-ranging in phase 2 trials: UNITE4TB and the MAMS-ROCI design | Angela Crook | |
| 5:26 PM | 0A07: Treatment outcome of all oral-short course regimens for RR-TB | Long-term outcomes in STREAM Stage 2: A phase 3 trial in rifampicin-resistant TB | Ruth Goodall | |
| Thursday 16 November | 10:38 AM | LB02: The Union/CDC late-breaker session on TB |
Efficacy and safety of levofloxacin preventive therapy in child and adolescent household contacts of multidrug-resistant tuberculosis: The TB-CHAMP double blind placebo-controlled, cluster randomised trial |
Anneke Hesseling |
| 6:38 PM | SS10 BENEFIT Kids: Better evidence and formulations to improve multidrug-resistant tuberculosis treatment in children | TB-CHAMP: efficacy and safety of levofloxacin for MDR-TB prevention for children | Anneke Hesseling | |
| Friday 17 November | 10:20 AM | SP28: An International Consensus on Early TB (ICE-TB) – the path to programmatic impact | An International Consensus for Early TB (ICE-TB): Results from the first Early TB Symposium | Asad Zaidi |
| 10:57 AM | Interventions for early TB: Developing interventions for a new framework | Hanif Esmail | ||
| 6:49 PM | SS17: Rethinking clinical trial design to accelerate improved treatment options for TB-affected communities | UNITE4TB-01: A new PARADIGM of evaluating novel drugs | Hanif Esmail |
Further information: