Our methodology research at the SCT annual conference 2023

19 May 2023

Sunday 21st May marks the beginning of the 44th Annual Meeting of the Society for Clinical Trials, where several researchers from the MRC Clinical Trials at UCL will be presenting their latest work.  

We will give a range of presentations on new developments in clinical trials methodology, including talks, discussions (both panel discussions and roundtable discussions) and a pre-conference workshop. 

SCT is an international organisation that advocates for the use of clinical trials to advance human health. Its members include representatives from academia, the pharmaceutical and device industries, government agencies, medical groups and centres, and clinical research entities. The SCT annual meeting is one of the largest gatherings of people to share research on how to improve clinical trials.

The conference will take place from Sunday 21 May to Wednesday 24 May in Baltimore, MD, USA.

The theme for this year’s meeting is “Championing high-quality evidence to optimise human health”. 

Details of the MRC CTU at UCL presentations taking place at the conference are shown below. 

  Time (ET) Session  Title Speaker Place
Statistical and practical aspects of the design and analysis of Multi-Arm Multi-Stage (MAMS) Platform Trials 

Babak Choodari-Oskooei

Max Parmar

Matt Sydes

Harborside Ballroom Salon E (Level 4)
Monday 22nd May  11:30AM – 12:45PM  ROUNDTABLE 6 Estimands in Clinical Trials  Brennan Kahan  Heron (Level 4)
12:45PM – 2:15PM  INVITED SESSION 6 Advancing Causal Inference Methods for Cluster Randomized Trials  Brennan Kahan  Harborside Ballroom Salon E (Level 4)
2:45AM - 4:15PM INVITED SESSION 9 The What and the How: Practical Challenges in Aligning Estimands and Estimation Using Tuberculosis as a Case Study  Tra My Pham  Harborside Ballroom Salons ABC (Level 4)
Tuesday 23rd May   9:30AM - 10:30AM  CONTRIBUTED SESSION 5: Reporting Methodology and Results of the CONSORT and SPIRIT Extensions for Factorial Trials Brennan Kahan  Harborside Ballroom Salons ABC (Level 4)
10:45AM- 11:45AM  CONTRIBUTED SESSION 7: MAMS/Adaptive  The Multi-Arm Multi-Stage Response Over Continuous Intervention (MAMS-ROCI) design: a practical design to optimise treatment administration Matteo Quartagno  Harborside Ballroom Salon E (Level 4) 
10:45AM - 11:45AM  CONTRIBUTED SESSION 7: MAMS/Adaptive  Optimizing multi-arm multi-stage platform randomised clinical trials in the phase III setting: with applications to the ROSSINI 2 (surgical) trial  Babak Choodari-Oskooei Harborside Ballroom Salon E (Level 4) 
10:45AM – 11:45AM  CONTRIBUTED SESSION 8: Survival Analysis 
Estimation of Restricted Mean Survival Time under proportional hazards in Non-Inferiority trials
Matteo Quartagno  Laurel (Level 4) 
2:30PM - 4PM  INVITED SESSION 15     
Academic-led trials for regulatory use

Max Parmar

Matt Sydes

Harborside Ballroom Salons ABC (Level 4) 


Check out the full programme on the SCT website or the #SCT2023 app.


MRC CTU at UCL attendees may be tweeting from: @mattsydes@stats_q@Brennan_Kahan@BabakOskooei@t_mpham, @MaxParmarMRCUCL

Further information: