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TB-CHAMP trial finds first-ever safe and effective treatment to prevent multidrug-resistant TB in children
The trial found that levofloxacin, taken for six months once daily, substantially reduced the risk of developing drug-resistant TB.
'25 at 25': Extending the use of drugs - repurposing and beyond
As the final instalment of our 25 at 25 series, we look back at some of the successes of trials we have run that have tested using drugs beyond their original licence.
'25 at 25': PROUD - preventing HIV infections
We look back on the remarkable success of the PROUD study as part of our ’25 at 25’ series celebrating the MRC Clinical Trials Unit’s 25th anniversary.